According to a report by Scott Wiltermuth, assistant professor of administration firm at the USC Marshall College of Business, and Vanessa K. Bohns, postdoctoral fellow at the J.L. Rotman School of Administration at the University of Toronto, adopting dominant versus submissive postures in fact reduces your sensitivity to discomfort. The study, ‘It Hurts When I REALLY DO This ‘ published in the Journal of Experimental Public Psychology, found that by simply adopting even more dominant poses, people feel better, in control and able to tolerate more distress. Out of the individuals studied, those who utilized the most dominant position could actually comfortably handle more pain than those designated a more neutral or submissive stance.The preliminary results of the analysis demonstrated that once daily administration of ALKS 33 was generally well tolerated at all three dose levels. While the difference in full abstinence from large drinking between treatment groups did not reach statistical significance, individuals treated with all three doses of ALKS 33 demonstrated a significant decrease in heavy drinking times in a dosage dependent manner in comparison to placebo. Patients on the highest dose of ALKS 33 demonstrated the greatest relative reduction in heavy drinking days of 41 percent compared to placebo.