Olson believes a high burden of stressful experiences in childhood could cause adjustments in how genes are expressed in later on life. He notes that earlier published research involving preclinical models suggest that may be the case but that additional human studies are required. Olson and Hegadoren desire to continue building upon the study to better predict which women will be vulnerable to preterm birth. In addition they hope to develop early interventions. If we know who is at risk, we are able to begin to treat them before the end of their pregnancy–and hopefully they'll have improved being pregnant outcomes. .. Adverse life events in childhood can easily increase woman’s risk of preterm birth Like most health professionals, David Olson has known for some right time of the dangers posed by excessive stress.After intensive therapy, glycated hemoglobin amounts had been 6.4 percent in the ACCORD and ADVANCE research and 6.9 percent in our study; after standard therapy, the values were 7.5 percent, 7.0 percent, and 8.4 percent, respectively. None of these studies showed a decrease in cardiovascular events. The rates of fat and hypoglycemia gain were higher in the intensive-therapy group in all three trials. In our study, we followed a human population of veterans for up to 7.5 years . Cardiovascular risk factors were controlled, and the between-group difference in glycated hemoglobin amounts was maintained.25,26 Microvascular complications were minimally suffering from intensive glucose control.